Properties of the peppermint will relieve itching and cool the aggravated skin. Tea Tree Oil in the shampoo has antifungal properties as well as being antiseptic. Another ingredient Citronella Oil is a natural plant based insect repellent. All Cain & Able Shampoos are Hypoallergenic and are safe for puppies. The shampoo is coconut based and all natural with no harsh detergents, synthetic perfumes, or artificial colors. The 16 oz. size includes a pump dispenser and is made in the USA.